InSilicoTrials-Led Consortium Secures Up to $30M ARPA-H Funding to Redefine Cardiac Drug Safety | StartUp Health Insights: Week of Dec 23, 2025
StartUp Health community member InSilicoTrials is leading a new consortium to help predict how a person’s heart will respond to a new medicine, one of the most persistent blind spots in drug development. It was part of a notably active and global week, with substantial investment flowing into AI, digital health, biotech, mental health, chronic care, and life sciences across almost a dozen countries.
Long-time StartUp Health community member InSilicoTrials has partnered with The Jackson Laboratory to lead CARDIOVERSE, a $30M initiative funded by ARPA-H through its CATALYST program to redefine cardiac drug safety with virtual heart models. Alongside The New York Stem Cell Foundation, UConn Health, and the University of Michigan this consortium will create the next generation of virtual heart models capable of representing the genetic, physiological, and demographic diversity of the American population, fundamentally transforming cardiac safety prediction. <source>
Other reported global health innovation funding this week included:
Tebra, a Newport Beach, CA-based EHR+ platform provider, raised $250M from Hildred, as well as a debt facility provided by J.P. Morgan, with participation from Montreux Growth Partners, Toba Capital, Transformation Capital, and HLM Venture Partners. <source>
Nanit, a New York, NY-based developer of AI-powered systems designed to provide parents with real-time insights into infant health and development, raised $50M led by Springcoast Partners, with participation from Upfront Ventures and JVP. <source>
Hyro, a New York, NY-based health tech startup tackling healthcare inefficiencies through voice AI agents, raised $45M Healthier Capital, Norwest, Define Ventures, Black Opal Ventures, and healthcare clients. <source>
Alaffia Health, a New York, NY-based AI-powered platform for optimizing claims operations for payers in the healthcare industry, raised $36M from undisclosed investors. <source>
Codoxo, a Duluth, GA-based provider of AI- and generative AI-powered healthcare payment integrity solutions, raised $35M led by CVS Health Ventures, with participation from Echo Health Ventures, Sands Capital, 111 West Capital, Brewer Lane Ventures, Wipro Ventures, 450 Ventures, and QED Investors. <source>
Neurable, a Boston, MA-based developer of AI brain-signal processing technology, raised $35M led by Spectrum Moonshot Fund. <source>
Truemed, an Austin, TX-based HSA/FSA marketplace for preventive health products, raised $34M led by Andreessen Horowitz, with participation from Bessemer Venture Partners, Long Journey Ventures, BoxGroup, and Trust Ventures. <source>
Manifold, a Newton, MA-based provider of an AI platform for life sciences, raised $18M led by Reach Capital, with participation from SilverArc Capital, Industry Ventures, TQ Ventures, and Calibrate Ventures. <source>
GravityLabs, a Seoul, South Korea- and San Francisco, CA-based AI-powered healthcare startup with a mission to extend humanity's healthy lifespan, raised $17M from SBVA, Goodwater Capital, Atinum Investment, NAVER, DSC Investment, and Bass Ventures. <source>
Ember LifeSciences, a Westlake Village, CA-based healthcare logistics technology company, raised $16.5M led by Sea Court Capital, with participation from Cardinal Health, Carrier Ventures, and others. <source>
Liom, a Schwyz, Switzerland-based developer of a non-invasive glucose-monitoring wearable, raised €13.9 ($16.4M) led by previous lead investors, with participation from Red Bull Ventures and individual investors. <source>
Drive Health, a Gilbert, AZ-based developer of a Google-powered agentic AI platform designed to transform how patients navigate care and alleviate the workload placed on clinicians, raised $15M from Vitalis Ventures. <source>
Clarity Pediatrics, a San Francisco, CA-based telehealth platform for pediatric chronic care, raised $14.5M led by Jackson Square Ventures, with participation from City Light Capital, MassMutual Catalyst Fund II, GingerBread Capital, Scrub Capital, Operator Collective, Rethink Impact, Maverick Ventures, and Homebrew. <source>
Leona Health, a Mexico City, Mexico-based AI co-pilot for doctors built on WhatsApp, raised $14M led by Andreessen Horowitz (a16z), with participation from General Catalyst, Accel, and individual investors. <source>
Wearlinq, a San Francisco, CA-based wireless cardiac monitor developer, raised $14M led by AIX Ventures. <source>
GlycanAge, a London, UK-based biotech startup building technology to make glycan biomarkers accessible in order to take actionable steps for healthier aging, raised $8.7M led by Fifth Quarter Ventures, with participation from Guinness Ventures, BrightCap Ventures, South Central Ventures, Impetus Capital, Vesna Deep Tech VC, Lightfield Equity, LaunchHub Ventures, and Kadmos Capital. <source>
Virohan, a Gurugram, India-based healthcare education startup, raised INR 65 Cr ($7.3M) led by Mynavi Corporation, with participation from Blume Ventures, Bharat Inclusive Technologies Seed Fund, and Rebright Partners. <source>
Vuno, a Seoul, South Korea-based company developing AI solutions that can analyze various types of data that are generated in medical settings, raised 10 billion KRW ($6.8M) from Smilegate Investment. <source>
Mindoo, a Brussels, Belgium-based provider of voice-first AI agents for hospital teams to handle structured intakes, documentation drafting, follow-up interactions, and front-desk communications, raised €5M ($5.9M) from 6DC, Syndicate One, and angel investors. <source>
CranioSense, a Bedford, MA-based neurotechnology company developing a noninvasive intracranial pressure diagnostic and monitoring system, raised $5.5M through the NIH Blueprint MedTech Program and the U.S. Department of Defense’s Joint Warfighter Medical Research Program (JWMRP). <source>
Arcreal, a Seoul, South Korea-based developer of a dental AI platform, raised 8 billion KRW ($5.4M) from DSC Investment, SDB Investment, Schmidt, and Soo Investment Capital. <source>
First Voyage, a New York, NY-based developer of an AI companion app for wellness habit-building, raised $2.5M led by a16z speedrun, with participation from SignalFire, True Global, and other investors. <source>
ANDHealth, a Melbourne, Australia-based provider of commercialization support and services to the digital and connected health sector, raised an undisclosed amount from the Victorian State Government. <source>
Automate.clinic, a Boulder, CO-based startup building clinical teams to train the next generation of healthcare AI, raised an undisclosed amount led by Matchstick Ventures and Headwater Ventures. <source>
Cosan, a Chicago, IL-based connected chronic care management company, raised an undisclosed amount from Ziegler Link-age Funds and The Specialty Alliance. <source>
PhyxUp Health, a San Jose, CA-based startup specializing in AI-powered remote therapeutic monitoring (RTM), raised an undisclosed amount from Korea Investment Accelerator and Synergy IB Investment. <source>
Data is from StartUp Health Insights, the most comprehensive funding database for health innovation. Sign up for StartUp Health Insider™ to get funding insights, news, and special updates delivered to your inbox.
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Published: Dec 23, 2025
By Nicole Kinsey
